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Interleukin-13

Struktur yang tersedia

Pencarian ortolog: PDBe RCSB

Daftar kode ID PDB
1GA3, 1IJZ, 1IK0, 3BPO, 3G6D, 3L5W, 3L5X, 3LB6, 4I77, 4PS4, 5E4E

Pengidentifikasi

Alias

IL13, IL-13, P600, interleukin 13

ID Eksternal

OMIM: 147683; MGI: 96541; HomoloGene: 1649; GeneCards: IL13; OMA:IL13 - orthologs

Pola ekspresi RNA

Bgee

Manusia

Tikus (ortologi)

n/a

Ekspresi tertinggi di

embrio

secondary oocyte

Zigot

seminiferous tubule

timus

spermatocyte

hippocampal formation

hippocampus proper

bibir

spermatid

BioGPS


Data ekspresi referensi lebih lanjut

Ontologi gen
Fungsi molekuler	Ikatan protein plasma cytokine receptor binding cytokine activity interleukin-13 receptor binding
Komponen seluler	sitoplasma external side of plasma membrane extracellular region extracellular space
Proses biologis	negative regulation of endothelial cell apoptotic process negative regulation of complement-dependent cytotoxicity negative regulation of transforming growth factor beta production positive regulation of lung goblet cell differentiation response to mechanical stimulus response to nicotine positive regulation of release of sequestered calcium ion into cytosol microglial cell activation negative regulation of NAD(P)H oxidase activity cellular response to mechanical stimulus response to lipopolysaccharide negative regulation of lung ciliated cell differentiation positive regulation of ion transport respons imun positive regulation of protein secretion positive regulation of connective tissue growth factor production positive regulation of pancreatic stellate cell proliferation response to ethanol inflammatory response regulation of proton transport positive regulation of smooth muscle cell proliferation negative regulation of neuron death positive regulation of immunoglobulin production positive regulation of B cell proliferation positive regulation of macrophage activation positive regulation of mast cell degranulation cellular response to cytokine stimulus positive regulation of tyrosine phosphorylation of STAT protein regulation of signaling receptor activity cytokine-mediated signaling pathway positive regulation of gene expression positive regulation of cold-induced thermogenesis
Sumber:Amigo / QuickGO

Ortologi

Spesies

Manusia

Tikus

Entrez


3596


16163

Ensembl


ENSG00000169194


ENSMUSG00000020383

UniProt


P35225


P20109

RefSeq (mRNA)


NM_002188


NM_008355

RefSeq (protein)


NP_002179 NP_001341920 NP_001341921 NP_001341922


NP_032381

Location (UCSC)

n/a

PubMed search

^[1]

^[2]

Wikidata

Lihat/Sunting Manusia

Lihat/Sunting Tikus

Interleukin-13, IL-13 adalah sebuah protein dengan fungsi sitokina yang disekresi berbagai sel, tetapi terutama oleh sel T_H2. Berbagai efek biologis IL-13, seperti halnya IL-4, terkait dengan sebuah faktor transkripsi yaitu STAT6.

Rujukan

↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

Hormon

Prekursor

DHEA · ProT · T4

T4 · T3 · T2 · T1

Glukokortikoid	Kortisol
Mineralokortikoid	Aldosteron

· CORT

Kalsitriol

Peptida

Faktor transkripsi	AP-1 · C/EBP-α · β · NF-κB · FLIP · STAT · 1 · 2 · 3 · 4 · 5 · 6

Insulin · CGRP · CRH · SREBP · Androgen · Estrogen · Pregnenolon · Progestagen · P4 · Testosteron

Ekstraselular

Glikoprotein

hCG · FSH · GPIHBP-1 · LH · TSH

Katekolamin

Adrenalin · PIH · Noradrenalin

Peptida

ACTH · AM · Angiotensin · CT · Gastrin · Glukagon · GnRH · GH · GHIH · GHRH · GHS · IAPP · OT · PRL · TRH · VP

Sitokin

Kemokina	C5a · CCL2 · CCL5 · GSM-CSF · LPS · MCP-1 · IL-1 · IL-2 · IL-3 · IL-4 · IL-5 · IL-6 · IL-8 · IL-10 · IL-12 · IL-13 · IL-15 · IL-18 · IP-10 · RETN