Gliese 581 (pengucapan:/ˈgliːzə/) atau HO Librae adalah bintangkatai merah dengan tipe spektrum M3V, terletak sejauh 20.3 tahun cahaya dari Bumi. Observasi menunjukan bahwa bintang ini diorbit oleh sedikitnya empat planet, yaitu Gliese 581 b, c, d, dan e. Bintang ini mendapat perhatian setelah Gliese 581 c, eksoplanet yang ditemukan terletak di dekat zona laik hidup bintang ini pada April 2007.
Pada akhir September 2010. telah dketemukan lagi dua planet yang mengelilingi bintang ini, yaitu Gliese 581 f dan g.
↑Samus, N. N.; Durlevich, O. V.; etal. (2009). "VizieR Online Data Catalog: General Catalogue of Variable Stars (Samus+ 2007–2013)". VizieR On-line Data Catalog: B/gcvs. Originally published in: 2009yCat....102025S. 1. Bibcode:2009yCat....102025S.
↑Selsis 3.4-page 1382 "lower limit of the age that, considering the associated uncertainties, could be around 7 Gyr", "preliminary estimate", "should not be above 10–11 Gyr"
↑In 1994 Edward Weis concluded that Gliese 581, like half the 43 dwarf M stars he studied over a multi-year period, showed long term variability (and page 1137, Fig 1 shows Gliese 581 had magnitude 10.58 in 1982 and between 10.57 and 10.56 from 1985 to 1990).[8] Bonfils noted in 2005 that Gliese 581 "has been classified as a variable star (HO Lib), but its variability (Weis 1994) is only marginally significant. If real it would be on a time scale of several years, with short term variability being at most ∼0.006 mag."[9] Measurements by MOST showed short term variability of about 5 mmag (half a percent) over a period of a few weeks.[10]